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These appetite changes start before dramatic weight appears on the scale

Weeks 5 to 8: building tolerance (0.50 mg per week) The first dose increase

It is expected to be commercially available in pharmacies in the second quarter of 2026

References Bergmann, N

Patients considering medically supervised weight loss should be aware of these restrictions: Section 503A pharmacies: Enforcement began April 22, 2025 Section 503B facilities: Must cease by May 22, 2025 Continued compounding may result in FDA enforcement actions Limited exceptions exist for documented allergies or specific medical needs Important Safety Note: The FDA strongly advises against using compounded semaglutide when FDA-approved alternatives are available

Semaglutide is a medication known as a GLP-1 receptor agonist